What do you get when Catherine Hardwicke makes a movie with Drew Barrymore and Toni Collette? A really great trailer, at the very least. The first look at Miss You Already, Hardwicke's dramedy about friendship, has landed. Barrymore and Collette play two lifelong buddies who see each other through all their ups and downs but are challenged when one of them is diagnosed with cancer. Dominic Cooper and Jacqueline Bisset costar in the movie, which comes out Nov.6. Stay tuned, and watch the trailer below!